[Download]Aortic valve neocuspidization using the Ozaki technique: A meta-analysis of reconstructed patient-level data [pdf]

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[Download]Aortic valve neocuspidization using the Ozaki technique: A meta-analysis of reconstructed patient-level data [pdf]

The  concept  of  the  ideal  cardiac  valve  prosthesis is predicated upon optimized hemodynamics, minimal postoperative morbidity, lasting durability, and ultimately prolonged patient survival with superior quality of life.  1  Mechanical  valves  require  lifelong  anticoagulation  and therefore  predispose  to  hemorrhagic  events.  On  the other hand, biological prostheses mount a chronic in- flammatory response, are prone to structural degenera- tion, and typically require a reintervention within 10 to 15 years.  2  Efforts to replace aortic valve (AV) tissue with biological material such as fascia lata and pericardium date back to the 1960s.  3-5  Ozaki  et  al  developed  their  AV  reconstruction  tech- nique at Toho University Ohashi Medical Center where they standardized the use of glutaraldehyde-treated au- tologous  pericardium to perform trileaflet aortic valve

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